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Particularly, nicotine has been the dominant candidate proposed to underlie the reduced risk of PD among smokers for nearly 50 years

In the United States alone, an estimated 316,950 women were diagnosed with breast cancer, and 42,170 died from the disease in 2025 ( Chemotherapy is a cornerstone in breast cancer treatment, employing cytotoxic agents to induce apoptosis and necrosis in cancer cells ( However, the cytotoxic effects of taxanes are not exclusive to malignant cells

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doi:10.1007/s11910-013-0394-8 Moharregh-Khiabani D, Linker RA, Gold R, Stangel M (2009) Fumaric Acid and its esters: an emerging treatment for multiple sclerosis